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Thermo Fisher Scientific Scientist III, Analytical Development in Saint Louis, Missouri

Job Title: Scientist III, Analytical Development

Work Location: St. Louis, MO

Division: Pharma Services Group (PSG)

What Will You Do?

Responsible for the development, evaluation and qualification of cell-based bioassays. Will perform testing to support process development and troubleshoot technical issues with method performance. Collaborates with Quality Control to transfer analytical methods within the ThermoFisher Scientific network. Makes detailed observations and analyzes, documents, and communicates test results.

Essential Functions:

  • Must have experience handling and maintaining mammalian cell cultures.

  • Deep understanding in cell and molecular biology.

  • Technical experience in cell-based assays (reporter gene assay, proliferation assay, and ADCC assay).

  • Preferably have experience using micro-titer plate readers and SoftMax software.

  • Working knowledge of ICH method validation guidance to assess method performance.

  • Designs experimental plans based on the defined deliverables.

  • Conducts moderately complex analyses to support process development.

  • Records results in notebook accurately, clearly, and regularly.

  • Prepares protocols, reports, and test methods and writes SOPs.

  • Maintains and ensures safe laboratory environment and work practices.

  • Executes appropriately record and evaluates experimental data, including the writing and revising of process development reports and technology transfer protocols as needed.

  • Remains current in the field by review of relevant scientific literature and attendance at appropriate scientific seminars and conferences.

How Will You Get There?

Education:

Bachelor's degree or Master's degree or PhD in biology, chemistry, biochemistry, chemical engineering, or a related field.

Experience:

With Bachelor's degree, minimum of 5 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory. Relevant industry and discipline experience preferred. Experience using design of experiments (DoE) software (i.e. MiniTab, JMP) preferred. With Master's degree, 3 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory. Relevant industry experience and discipline preferred. Experience using advanced statistical software packages and experience using design of experiments (DoE) software (i.e. MiniTab, JMP) preferred. With PhD, experience with practical scientific application necessary, though related experience not necessary.

Equivalency :

Equivalent combinations of education, training, and relevant work experience may be considered.

Competencies:

Deep knowledge of varied aspects or a specialized aspect of discipline. Working knowledge of GMP/ GLP regulations in cGMP/ cGLP manufacturing environment. Excellent problem solving and critical thinking skills. Solid writing, communication and presentation skills. Strong MS Excel, PowerPoint and Word skills. Excellent organization and planning skills. Strong attention to detail and ability to adhere to standards procedures. Ability to design and execute tasks and studies based on the deliverables. Ability to analyze and summarize complex scientific data. Ability to create reports. Ability to function in a rapidly changing environment. Strong attention to detail and ability to adhere to standards procedures. Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations. Ability to speak effectively before groups of customers and employees. Ability to make decisions that require choosing between limited alternatives to resolve complex problems. Ability to perform all required process steps. Ability to apply complex mathematical concepts to physical problems in areas. Ability to lead and mentor less experienced staff.

Physical Requirements:

Position requires ordinary ambulatory skills and physical coordination sufficient to move about office locations; ability to stand, walk, stoop, kneel, crouch periodically for prolonged periods of time; manipulation (lift, carry, move) of light to medium weights of 10-35 pound pounds; arm, hand and finger dexterity, including ability to grasp and type for prolonged periods of time; visual acuity to use a keyboard, computer monitor, operate equipment, and read materials for prolonged periods of time; ability to sit, reach with hands and arms, talk, and hear for prolonged periods of time. Lift objects up to 50 lbs. to a cart and push cart short distances on a regular basis. Stand up to 50% daily. Walk within lab and between buildings daily. Repetitive hand motions.

Disclaimer:

This job description is intended to present the general content and requirements for the performance of this job. The description is not to be construed as an exhaustive statement of duties, responsibilities, or requirements. Managers and supervisors may assign other duties as needed.

Nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees.

Thermo Fisher Scientific is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, creed, religion, color, national or ethnic origin, citizenship, sex, sexual orientation, gender identity and expression, genetic information, veteran status, age or disability status.

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